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Nystatin

Function

  • have disinfectant effect
  • Mainly used for skin and mucous membrane, oral cavity, intestinal and vaginal white candida infection, high concentration of sterilization Polyene antifungal antibiotics
  • Polyene antifungal antibiotics

Product Name: Nystatin
CAS: 1400-61-9
MF: C47H75NO17
MW: 926.09
EINECS: 215-749-0
Nystatin Usage And Synthesis
Chemical Properties Brown Solid
Usage Antifungal;Performs membrane ionophores

CERTIFICATE OF ANALYSIS
Product name
Nystatin
CAS No.
1400-61-9
Outer Packing
 drum
Production date
2017-03-14
Shelf life
2020-0313
Standard adopted
USP&EP
Items of analysis
Specification
Results
Appearance
a yellow or slightly brownis powder
Conforms
Description
With a characteristic odor, soluble in dimethylformamide, slightly soluble in methanol, almost insoluble in water, alcohol and ether
Conforms
UV spectroscopy A230 nm/A279nm
0.90-1.25
1.06
UV spectroscopy A291 nm/A305nm
0.61-0.73
0.66
UV spectroscopy A319nm/A305nm
0.83-0.96
0.92
UV spectroscopy A230 nm/A280nm
0.83-1.25
1.04
Potency(USP)
≥5000u/mg
6760u/mg
Loss on drying
≤5.0%
4.0%
sulphated ash
≤3.5%
0.2%
absorbance at 305nm
≥0.60
0.85
Heavy metals
≤20ppm
Conforms
PH
6.0-8.0
7.7
Total aerobic bacteria
≤1000 CFU/g
<5
yeast and moilds
≤100 CFU/g
<5
Composition HPLC:Nystatin A1
≥85.0%
91.2%
Any ather compound
≤4.0%
1.3%
Conclusion
Qualified

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