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Loratadine

Function  :

Antihistamines
Allergy drug
Respiratory system and anti-allergic drugs
Intermediates
Pharmaceutical intermediates

Product Name: Loratadine
CAS: 79794-75-5
MF: C22H23ClN2O2
MW: 382.88
MP: 134-136°C
Storage temp: 2-8°C
Solubility DMSO: 26 mg/mL, soluble
Form: powder
Color: white
Stability: Stable, but may be heat sensitive – refrigerate. Incompatible with strong oxidizing agents.
Chemical Properties: White Crystalline Solid

               CERTIFICATE OF ANALYSIS

Product name
Loratadine
CAS No.
79794-75-5
Outer Packing
1 kg or a drum
Production date
2015.06.05
Shelf life
2020.06.02
Standard
Enterprise Standard
Items of analysis
Specification
Results
Appearance
White to white powder
White to white powder
Solubleness
Soluble in acetone, methanol, toluene, chloroform; Does not dissolve in water
confrom
Melting point
132-137℃
132.5-135.8℃
Identify
Comply with the standard
complies
PB
≤10ppm
complies
individual impurity
≤0.1%
0.062%
Total impurity
≤0.3%
0.13%
ignition residue
≤0.1%
0.05%
Loss on drying
≤0.5%
0.23%
Assay
98.5-101%
99.29%
Conclusion
Qualified

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